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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM3020Similar to E. coli putative transcriptional regulator LYSR-type (AAC73606.1); Blastp hit to AAC73606.1 (308 aa), 26% identity in aa 2 - 275; Belongs to the LysR transcriptional regulatory family. (287 aa)    
Predicted Functional Partners:
STM4067
Putative ADP-ribosylglycohydrolase; Similar to E. coli orf, hypothetical protein (AAC75160.1); Blastp hit to AAC75160.1 (334 aa), 30% identity in aa 108 - 325, 32% identity in aa 5 - 188.
   
  
 0.900
STM3021
Putative inner membrane protein.
 
     0.823
rpoZ
RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
      
 0.760
STM2180
Similar to E. coli putative transcriptional regulator LYSR-type (AAC74504.1); Blastp hit to AAC74504.1 (354 aa), 28% identity in aa 54 - 336; Belongs to the LysR transcriptional regulatory family.
  
     0.754
STM4270
Putative LysR family transcriptional regulator; Similar to E. coli activator, hydrogen peroxide-inducible genes (AAC76943.1); Blastp hit to AAC76943.1 (305 aa), 28% identity in aa 1 - 275; Belongs to the LysR transcriptional regulatory family.
  
    0.742
efp
Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
      
 0.700
xapR
Regulator for XapA; LysR family; similar to E. coli regulator for xapA (AAC75458.1); Blastp hit to AAC75458.1 (294 aa), 80% identity in aa 1 - 293; Belongs to the LysR transcriptional regulatory family.
  
     0.688
STM2575
Putative LysR family transcriptional regulator; Similar to E. coli cyn operon positive regulator (AAC73441.1); Blastp hit to AAC73441.1 (299 aa), 30% identity in aa 4 - 229; Belongs to the LysR transcriptional regulatory family.
  
     0.688
ydcI
Similar to E. coli putative transcriptional regulator LYSR-type (AAC74504.1); Blastp hit to AAC74504.1 (354 aa), 83% identity in aa 48 - 353; Belongs to the LysR transcriptional regulatory family.
  
     0.666
STM0692
Putative LysR family transcriptional regulator; Similar to E. coli nitrogen assimilation control protein (AAC75050.1); Blastp hit to AAC75050.1 (305 aa), 32% identity in aa 1 - 301; Belongs to the LysR transcriptional regulatory family.
  
     0.658
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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