STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yohMPutative inner membrane protein; Efflux system for nickel and cobalt. (288 aa)    
Predicted Functional Partners:
yohL
Putative cytoplasmic protein; Repressor of rcnA expression. Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt. In the presence of one of these metals, it has a weaker affinity for rcnA promoter (By similarity); Belongs to the FrmR/RcnR family.
 
   
 0.991
nikR
Nickel-responsive transcriptional regulator; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.
  
   
 0.783
bigA
Putative surface-exposed virulence protein BigA (gi|5081595).
  
  
 0.741
zntA
P-type ATPase family; Pb/Cd/Zn/Hg transporting ATPase; similar to E. coli zinc-transporting ATPase (AAC76494.1); Blastp hit to AAC76494.1 (732 aa), 84% identity in aa 1 - 731.
     
 0.725
znuA
ABC superfamily high affinity Zn transport protein; Binding protein; similar to E. coli putative adhesin (AAC74927.1); Blastp hit to AAC74927.1 (328 aa), 85% identity in aa 1 - 328.
     
 0.716
ygiX
Putative transcriptional regulator; Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of flhDC (By similarity).
      
 0.716
yqjI
Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC76106.1); Blastp hit to AAC76106.1 (207 aa), 68% identity in aa 1 - 207.
      
 0.700
ygiY
Putative sensory histidine kinase in regulatory system; Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of FlhDC. May activate QseB by phosphorylation (By similarity).
      
 0.671
ygbF
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75796.1); Blastp hit to AAC75796.1 (116 aa), 84% identity in aa 23 - 116.
      
 0.577
ybjY
Similar to E. coli putative membrane protein (AAC73965.1); Blastp hit to AAC73965.1 (380 aa), 83% identity in aa 12 - 378; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.576
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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