STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tnpA_4Transposase for insertion sequence element is200 (SW:T200_SALTY). (152 aa)    
Predicted Functional Partners:
STM1228
Putative periplasmic protein.
      
 0.945
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
      
 0.671
STM0291
Putative RHS-family protein; Similar to E. coli rhsD protein in rhs element (AAC73599.1); Blastp hit to AAC73599.1 (1426 aa), 27% identity in aa 315 - 985, 46% identity in aa 1151 - 1261, 25% identity in aa 297 - 788, 24% identity in aa 346 - 870, 22-1073758628dentity in aa 465 - 904, 26% identity in aa 317 - 724, 32-1073758654dentity in aa 4 - 143, 24% identity in aa 232 - 605, 21% identity in aa 562 - 970, 23% identity in aa 318 - 755, 32% identity in aa 974 - 1076, 26% identity in aa 935 - 1051, 22% identity in aa 358 - 540, 37% identity in aa 1 - 32, 31-1073758588dentity in aa 1041 [...]
     
 0.631
prpB
Putative carboxyphosphonoenolpyruvate mutase; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2- methylisocitrate to yield pyruvate and succinate via an alpha-carboxy- carbanion intermediate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
   
  
 0.548
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (26%) [HD]