Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
STM3083Putative mannitol dehydrogenase; Similar to E. coli putative oxidoreductase (AAC75233.1); Blastp hit to AAC75233.1 (488 aa), 49% identity in aa 1 - 477; Belongs to the mannitol dehydrogenase family. (490 aa)    
Predicted Functional Partners:
mtlA
Similar to E. coli PTS system, mannitol-specific enzyme IIABC components (AAC76623.1); Blastp hit to AAC76623.1 (637 aa), 95% identity in aa 1 - 637.
  
  
 0.942
STM3081
Similar to E. coli putative malate dehydrogenase (AAC73619.1); Blastp hit to AAC73619.1 (349 aa), 40% identity in aa 3 - 332; L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family.
  
    0.908
STM3082
Putative zinc-binding dehydrogenase; Similar to E. coli putative oxidoreductase (AAC77314.1); Blastp hit to AAC77314.1 (345 aa), 54% identity in aa 9 - 345.
  
  
 0.839
uxuA
Putative mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
 0.806
uxaC
Similar to E. coli uronate isomerase (AAC76127.1); Blastp hit to AAC76127.1 (470 aa), 67% identity in aa 1 - 468.
 
 
 0.729
STM4448
Putative phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
  
  
 0.701
rspA
Putative dehydratase; Similar to E. coli starvation sensing protein (AAC74653.1); Blastp hit to AAC74653.1 (404 aa), 94% identity in aa 1 - 404.
 
  
 0.683
STM3080
Putative mannitol dehydrogenase; Similar to E. coli orf, hypothetical protein (AAC77209.1); Blastp hit to AAC77209.1 (153 aa), 38% identity in aa 4 - 150.
  
    0.674
kdgK
Similar to E. coli ketodeoxygluconokinase (AAC76551.1); Blastp hit to AAC76551.1 (382 aa), 92% identity in aa 74 - 381.
 
   
 0.585
fruF
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.
  
  
 0.567
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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