STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sprTPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75981.1); Blastp hit to AAC75981.1 (165 aa), 90% identity in aa 1 - 164; Belongs to the SprT family. (165 aa)    
Predicted Functional Partners:
STM1675
Putative short-chain alcohol dehydrogenase; Similar to E. coli putative oxidoreductase (AAC77206.1); Blastp hit to AAC77206.1 (237 aa), 80% identity in aa 1 - 237.
      
 0.897
yciS
Putative inner membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.767
yggJ
Putative cytoplasmic protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
     
 0.744
endA
Similar to E. coli DNA-specific endonuclease I (AAC75982.1); Blastp hit to AAC75982.1 (235 aa), 87% identity in aa 1 - 235.
     
 0.741
gshB
Similar to E. coli glutathione synthetase (AAC75984.1); Blastp hit to AAC75984.1 (316 aa), 90% identity in aa 1 - 313.
       0.694
spr
Putative lipoprotein; Suppresses thermosensitivity of prc mutants at low osmolality; similar to E. coli putative lipoprotein (AAC75236.1); Blastp hit to AAC75236.1 (188 aa), 92% identity in aa 1 - 188.
      
 0.672
yjaG
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76973.1); Blastp hit to AAC76973.1 (196 aa), 94% identity in aa 1 - 196; To H.influenzae HI_0431.
  
     0.625
cydD
Cytochrome-related transporter; Zn sensitive; ABC superfamily (atp&memb); similar to E. coli ATP-binding component of cytochrome-related transport, Zn sensitive (AAC73973.1); Blastp hit to AAC73973.1 (588 aa), 90% identity in aa 1 - 588.
  
   
 0.608
rseA
Anti sigma E (sigma 24) factor, negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytop [...]
  
     0.606
galP
MFS family galactose:proton symporter; Similar to E. coli galactose-proton symport of transport system (AAC75980.1); Blastp hit to AAC75980.1 (464 aa), 97% identity in aa 1 - 464; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
       0.605
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.