STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
endASimilar to E. coli DNA-specific endonuclease I (AAC75982.1); Blastp hit to AAC75982.1 (235 aa), 87% identity in aa 1 - 235. (235 aa)    
Predicted Functional Partners:
yggJ
Putative cytoplasmic protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
 
  
 0.930
sprT
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75981.1); Blastp hit to AAC75981.1 (165 aa), 90% identity in aa 1 - 164; Belongs to the SprT family.
  
  
 0.874
hsdS
Specificity determinant for hsdM and hsdR; The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site. Whether the DNA is cut or modified depends on the methylation state of the target sequence. When the target site is unmodified, the DNA is cut. When the target site is hemimethylated, the complex acts as a maintenance M [...]
  
  
 0.826
gshB
Similar to E. coli glutathione synthetase (AAC75984.1); Blastp hit to AAC75984.1 (316 aa), 90% identity in aa 1 - 313.
       0.803
yggL
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75996.1); Blastp hit to AAC75996.1 (118 aa), 95% identity in aa 11 - 118.
      
 0.767
yhfL
Putative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC76394.1); Blastp hit to AAC76394.1 (55 aa), 81% identity in aa 1 - 54.
      
 0.767
yihG
Similar to E. coli putative endonuclease (AAC76860.1); Blastp hit to AAC76860.1 (310 aa), 82% identity in aa 10 - 307.
   
  
 0.676
rpsL
30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.
   
  
 0.547
yhcR
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76274.1); Blastp hit to AAC76274.1 (90 aa), 98% identity in aa 24 - 90.
      
 0.546
yqgE
Putative transcriptional regulator; Similar to E. coli orf, hypothetical protein (AAC75985.1); Blastp hit to AAC75985.1 (211 aa), 92% identity in aa 25 - 211; Belongs to the UPF0301 (AlgH) family.
       0.535
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.