Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM3121Putative transcriptional regulator (gi|5852589); Belongs to the LysR transcriptional regulatory family. (292 aa)    
Predicted Functional Partners:
STM3119
Putative monoamine oxidase; Similar to E. coli putative aldehyde dehydrogenase (AAC74469.1); Blastp hit to AAC74469.1 (681 aa), 29% identity in aa 530 - 661.
  
  
 0.959
STM3120
Putative LysR family transcriptional regulator; Similar to E. coli citrate lyase beta chain (acyl lyase subunit) (AAC73717.1); Blastp hit to AAC73717.1 (307 aa), 31% identity in aa 20 - 299; Belongs to the HpcH/HpaI aldolase family.
  
  
 0.958
STM3118
Putative acetyl-CoA hydrolase; Similar to E. coli putative coenzyme A transferase (AAC75957.1); Blastp hit to AAC75957.1 (492 aa), 27% identity in aa 187 - 458, 24% identity in aa 8 - 169.
  
  
 0.948
STM3117
Putative lactoylglutathione lyase; Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidoglycan layer of the cell wall.
     
 0.929
STM2240
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74633.1); Blastp hit to AAC74633.1 (362 aa), 84% identity in aa 251 - 362, 43% identity in aa 14 - 238.
   
  
 0.864
STM3123
Similar to E. coli putative arylsulfatase regulator (AAC76803.1); Blastp hit to AAC76803.1 (411 aa), 36% identity in aa 4 - 248, 34% identity in aa 230 - 387.
   
  
 0.861
STM3777
Putative cytoplasmic protein.
   
  
 0.856
STM4489
Putative superfamily I DNA helicases; Similar to E. coli putative frameshift suppressor (AAC77264.1); Blastp hit to AAC77264.1 (338 aa), 68% identity in aa 1 - 338.
      
 0.854
STM4449
Putative copG family helix-turn-helix protein; Similar to E. coli negative regulator of translation (AAC74637.1); Blastp hit to AAC74637.1 (79 aa), 46% identity in aa 1 - 79.
      
 0.853
yifA
Putative LysR family transcriptional regulator; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
  
     0.761
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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