STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM3134Putative permease; Similar to E. coli transport of hexuronates (AAC76128.1); Blastp hit to AAC76128.1 (472 aa), 47% identity in aa 43 - 454. (434 aa)    
Predicted Functional Partners:
uxuA
Putative mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
  
 0.948
uhpC
Regulator of uhpT expression; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. UhpC senses external glucose-6-phosphate and interacts with the histidine kinase UhpB, leading to the stimulation of the autokinase activity of UhpB. Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
  
   
 0.916
STM3169
Similar to E. coli putative solute-binding transport protein (AAC76603.1); Blastp hit to AAC76603.1 (328 aa), 28% identity in aa 7 - 320.
   
  
 0.899
ygiK
Putative integral membrane protein; Possible transporter; hypothetical 46.1 Kda protein in plsC 3'region. (SW:YGIK_SALTY).
   
  
 0.899
uxaC
Similar to E. coli uronate isomerase (AAC76127.1); Blastp hit to AAC76127.1 (470 aa), 67% identity in aa 1 - 468.
 
  
 0.883
dgoK
Similar to E. coli 2-oxo-3-deoxygalactonate kinase (AAC76716.1); Blastp hit to AAC76716.1 (292 aa), 81% identity in aa 1 - 292.
  
  
 0.838
dgoA
Galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate.
  
  
 0.806
yiiZ
Putative dicarboxylate-binding periplasmic protein; Hypothetical protein in sodA 5'region. (SW:YIIZ_SALTY).
   
  
 0.766
uhpT
MFS family hexose phosphate transport protein; Mediates the exchange of external hexose 6-phosphate and internal inorganic phosphate.
  
   
 0.642
STM0520
Similar to E. coli putative transport protein, cryptic, orf, joins former yjiZ and yjjL (AAC77312.1); Blastp hit to AAC77312.1 (453 aa), 24% identity in aa 40 - 439.
  
     0.638
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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