STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM3136Similar to E. coli D-mannonate oxidoreductase (AAC77279.1); Blastp hit to AAC77279.1 (486 aa), 79% identity in aa 4 - 486; Belongs to the mannitol dehydrogenase family. (490 aa)    
Predicted Functional Partners:
uxuA
Putative mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
 0.998
uxaC
Similar to E. coli uronate isomerase (AAC76127.1); Blastp hit to AAC76127.1 (470 aa), 67% identity in aa 1 - 468.
 
 
 0.994
mtlA
Similar to E. coli PTS system, mannitol-specific enzyme IIABC components (AAC76623.1); Blastp hit to AAC76623.1 (637 aa), 95% identity in aa 1 - 637.
  
  
 0.951
rspA
Putative dehydratase; Similar to E. coli starvation sensing protein (AAC74653.1); Blastp hit to AAC74653.1 (404 aa), 94% identity in aa 1 - 404.
 
  
 0.935
rspB
Putative dehydrogenase; Similar to E. coli starvation sensing protein (AAC74652.1); Blastp hit to AAC74652.1 (339 aa), 75% identity in aa 1 - 339.
  
 
 0.903
ydfI
Putative mannitol dehydrogenase; Similar to E. coli putative oxidoreductase (AAC74615.1); Blastp hit to AAC74615.1 (486 aa), 81% identity in aa 1 - 484; Belongs to the mannitol dehydrogenase family.
  
  
 
0.903
STM4448
Putative phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
  
  
 0.755
STM0650
Similar to E. coli putative hydrolase (AAC76162.1); Blastp hit to AAC76162.1 (523 aa), 35% identity in aa 167 - 521, 32% identity in aa 119 - 223.
 
 0.687
kdgK
Similar to E. coli ketodeoxygluconokinase (AAC76551.1); Blastp hit to AAC76551.1 (382 aa), 92% identity in aa 74 - 381.
 
  
 0.662
fruF
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.
  
  
 0.591
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.