STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hybCSimilar to E. coli probable large subunit, hydrogenase-2 (AAC76030.1); Blastp hit to AAC76030.1 (567 aa), 94% identity in aa 1 - 567. (567 aa)    
Predicted Functional Partners:
hybB
Similar to E. coli probable cytochrome Ni/Fe component of hydrogenase-2 (AAC76031.1); Blastp hit to AAC76031.1 (392 aa), 96% identity in aa 1 - 392.
 
 
 0.999
hybA
Unknown; Intitally thought to be hydrogenase-2 small subunit which now identified as hybO; similar to E. coli hydrogenase-2 small subunit (AAC76032.1); Blastp hit to AAC76032.1 (328 aa), 95% identity in aa 1 - 328.
 
 
 0.999
hypO
Putative Ni/Fe hydrogenases, small subunit; Similar to E. coli putative hydrogenase subunit (AAC76033.1); Blastp hit to AAC76033.1 (372 aa), 96% identity in aa 1 - 372.
 
 0.999
hybD
Similar to E. coli probable processing element for hydrogenase-2 (AAC76029.1); Blastp hit to AAC76029.1 (164 aa), 94% identity in aa 1 - 163.
 
  
 0.997
STM1539
Similar to E. coli hydrogenase-1 small subunit (AAC74057.1); Blastp hit to AAC74057.1 (372 aa), 72% identity in aa 1 - 371.
 
 0.990
STM1786
Similar to E. coli hydrogenase-1 small subunit (AAC74057.1); Blastp hit to AAC74057.1 (372 aa), 92% identity in aa 1 - 372.
 
 0.990
hybE
Putative hydrogenase; Similar to E. coli member of hyb operon (AAC76028.1); Blastp hit to AAC76028.1 (162 aa), 80% identity in aa 1 - 162.
 
  
 0.971
hybF
Putative hydrogenase expression/formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.952
hybG
Similar to E. coli hydrogenase-2 operon protein: may effect maturation of large subunit of hydrogenase-2 (AAC76026.1); Blastp hit to AAC76026.1 (82 aa), 93% identity in aa 1 - 82.
 
 
 0.909
STM1787
Similar to E. coli hydrogenase-1 large subunit (AAC74058.1); Blastp hit to AAC74058.1 (597 aa), 91% identity in aa 1 - 597.
  
  
 
0.907
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.