Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yqhCPutative AraC/XylS family transcriptional regulator; Similar to E. coli putative ARAC-type regulatory protein (AAC76046.1); Blastp hit to AAC76046.1 (375 aa), 83% identity in aa 72 - 375. (305 aa)    
Predicted Functional Partners:
yqhD
Putative alcohol dehydrogenase; Similar to E. coli putative oxidoreductase (AAC76047.1); Blastp hit to AAC76047.1 (387 aa), 88% identity in aa 1 - 387.
  
  
 0.934
yqhE
2,5-diketo-D-gluconate reductase A; Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).
  
  
 0.767
agaR
Aga operon transcriptional repressor; DeoR family; similar to E. coli putative DEOR-type transcriptional regulator of aga operon (AAC76165.1); Blastp hit to AAC76165.1 (269 aa), 26% identity in aa 10 - 252.
      
 0.726
araC
Transcriptional regulator (AraC/XylS family) for ara operon; Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose.
  
  
 0.612
soxS
Transcriptional activator of superoxide response regulon; Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters (By similarity).
  
   
 0.597
marA
AraC/XylS family transcriptional activator of defense systems; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF.
  
     0.531
pocR
Propanediol utilization protein; Positive regulatory protein of pdu and cob operons.
  
    0.504
STM0581
Putative regulatory protein; Resistance against oxidative stress protein A (gi|9885772).
  
  
 0.498
nemA
Similar to E. coli N-ethylmaleimide reductase (AAC74722.1); Blastp hit to AAC74722.1 (365 aa), 92% identity in aa 1 - 365.
  
  
 0.454
rob
Transcriptional regulator; AraC/XylS family; similar to E. coli right origin-binding protein (AAC77349.1); Blastp hit to AAC77349.1 (289 aa), 92% identity in aa 1 - 289.
  
     0.426
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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