STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdaBNADPH specific quinone oxidoreductase; Drug modulator; similar to E. coli modulator of drug activity B (AAC76064.1); Blastp hit to AAC76064.1 (193 aa), 92% identity in aa 1 - 192. (193 aa)    
Predicted Functional Partners:
ygiN
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76065.1); Blastp hit to AAC76065.1 (104 aa), 90% identity in aa 1 - 104.
 
  
 0.986
ygiY
Putative sensory histidine kinase in regulatory system; Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of FlhDC. May activate QseB by phosphorylation (By similarity).
 
  
 0.861
STM3175
Putative bacterial regulatory helix-turn-helix protein; araC family; similar to E. coli orf, hypothetical protein (AAC76059.1); Blastp hit to AAC76059.1 (160 aa), 54% identity in aa 6 - 159.
  
  
 0.799
yieF
Putative oxidoreductase; Similar to E. coli orf, hypothetical protein (AAC76736.1); Blastp hit to AAC76736.1 (188 aa), 92% identity in aa 1 - 187.
     
 0.767
ygiX
Putative transcriptional regulator; Member of a two-component regulatory system QseB/QseC. Activates the flagella regulon by activating transcription of flhDC (By similarity).
 
  
 0.715
kefC
CPA2 family K+ efflux antiporter, glutathione-regulated; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
 
 
 0.693
kefB
CPA2 family K+:H+ antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
 
 
 0.693
bcp
Thioredoxin dependent thiol peroxidase; Similar to E. coli bacterioferritin comigratory protein (AAC75533.1); Blastp hit to AAC75533.1 (156 aa), 98% identity in aa 1 - 156.
      
 0.690
STM1731
Putative catalase (gi|7162108).
      
 0.673
STM1252
Putative cytoplasmic protein.
      
 0.650
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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