Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ygjRPutative dehydrogenase; Similar to E. coli orf, hypothetical protein (AAC76122.1); Blastp hit to AAC76122.1 (334 aa), 83% identity in aa 7 - 332. (332 aa)    
Predicted Functional Partners:
ybiI
Putative DnaK suppressor protein; Similar to E. coli orf, hypothetical protein (AAC73890.1); Blastp hit to AAC73890.1 (88 aa), 80% identity in aa 1 - 88.
      
 0.897
ycgB
Similar to E. coli putative sporulation protein (AAC74272.1); Blastp hit to AAC74272.1 (510 aa), 96% identity in aa 1 - 510.
   
  
 0.820
ygjQ
Putative integral membrane protein; Similar to E. coli orf, hypothetical protein (AAC76121.1); Blastp hit to AAC76121.1 (230 aa), 73% identity in aa 1 - 230.
       0.572
lysS
Similar to E. coli lysine tRNA synthetase, constitutive; suppressor of ColE1 mutation in primer RNA (AAC75928.1); Blastp hit to AAC75928.1 (505 aa), 95% identity in aa 1 - 505; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.512
ygjP
Putative metal-dependent hydrolase; Similar to E. coli orf, hypothetical protein (AAC76120.1); Blastp hit to AAC76120.1 (179 aa), 88% identity in aa 13 - 174.
       0.501
mviM
Virulence factor MVIM. (SW:MVIM_SALTY); Belongs to the Gfo/Idh/MocA family.
  
  
 0.493
yhcP
Putative inner membrane protein; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
  
    0.453
mukB
Kinesin-line cell division protein involved in sister chromosome partitioning; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.
  
     0.443
ygjT
Putative resistance protein; Has been proposed to be a redox modulator. Belongs to the TerC family.
       0.439
ygjO
Putative methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
 
     0.408
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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