STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhaLPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76142.1); Blastp hit to AAC76142.1 (56 aa), 70% identity in aa 3 - 56. (54 aa)    
Predicted Functional Partners:
phoL
Putative phosphate starvation-inducible protein, ATP-binding; Similar to E. coli putative ATP-binding protein in pho regulon (AAC73761.1); Blastp hit to AAC73761.1 (359 aa), 96% identity in aa 1 - 359.
      
 0.897
ybeD
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73732.1); Blastp hit to AAC73732.1 (87 aa), 97% identity in aa 1 - 87; Belongs to the UPF0250 family.
      
 0.892
ycaR
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74003.1); Blastp hit to AAC74003.1 (60 aa), 93% identity in aa 1 - 60; Belongs to the UPF0434 family.
      
 0.837
yheM
Putative oxidation of intracellular sulfur; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
      
 0.833
yheN
Putative ACR involved in intracellular sulfur reduction; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.
   
  
 0.820
yigP
Putative inner membrane protein; Required for ubiquinone (coenzyme Q) biosynthesis under aerobic conditions. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex (By similarity). May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates (By similarity). Required for intracellular proliferation in macrophages. Belongs to the UbiJ family.
      
 0.808
ycdC
Putative transcriptional repressor (TetR/AcrR family); Similar to E. coli putative tet operon regulator (AAC74098.1); Blastp hit to AAC74098.1 (212 aa), 83% identity in aa 1 - 212.
      
 0.800
ybaB
Putative cytoplasmic protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
      
 0.766
ygfZ
Putative aminomethyltransferase; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family.
      
 0.764
yhaK
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76141.1); Blastp hit to AAC76141.1 (233 aa), 84% identity in aa 1 - 233; Belongs to the pirin family.
       0.757
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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