STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhaOSimilar to E. coli putative transport system permease protein (AAC76145.1); Blastp hit to AAC76145.1 (425 aa), 97% identity in aa 3 - 425. (443 aa)    
Predicted Functional Partners:
yhaN
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76143.1); Blastp hit to AAC76143.1 (188 aa), 92% identity in aa 1 - 187; Belongs to the UPF0597 family.
 
  
 0.988
alaE
Putative inner membrane protein; Exports L-alanine; Belongs to the AlaE exporter family.
      
 0.725
yfiK
Putative transport protein; Exporter of O-acetylserine (OAS) and cysteine; Belongs to the Rht family.
   
  
 0.678
yhaJ
Similar to E. coli putative transcriptional regulator LYSR-type (AAC76140.1); Blastp hit to AAC76140.1 (298 aa), 96% identity in aa 1 - 298; Belongs to the LysR transcriptional regulatory family.
      
 0.655
tdcC
HAAAP family L-threonine/ L-serine permease; Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
 
   
0.507
dps
Stress response DNA-binding protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
    
   0.504
yrbL
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76239.1); Blastp hit to AAC76239.1 (210 aa), 77% identity in aa 1 - 210.
  
 0.464
ygiW
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC76060.1); Blastp hit to AAC76060.1 (130 aa), 89% identity in aa 1 - 130.
  
     0.450
tdcG
Similar to E. coli L-serine dehydratase (deaminase), L-SD2 (AAC75839.1); Blastp hit to AAC75839.1 (455 aa), 74% identity in aa 1 - 452; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
  
 0.447
yccD
Putative cytoplasmic protein; Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ.
  
     0.415
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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