node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ilvB | ilvE | STM3796 | STM3903 | Valine sensitive; similar to E. coli acetolactate synthase I,valine-sensitive, large subunit (AAC76694.1); Blastp hit to AAC76694.1 (562 aa), 91% identity in aa 1 - 562. | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. | 0.824 |
ilvB | ilvH | STM3796 | STM0117 | Valine sensitive; similar to E. coli acetolactate synthase I,valine-sensitive, large subunit (AAC76694.1); Blastp hit to AAC76694.1 (562 aa), 91% identity in aa 1 - 562. | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | 0.999 |
ilvB | ilvI | STM3796 | STM0116 | Valine sensitive; similar to E. coli acetolactate synthase I,valine-sensitive, large subunit (AAC76694.1); Blastp hit to AAC76694.1 (562 aa), 91% identity in aa 1 - 562. | Acetolactate synthase isozyme III large subunit. (SW:ILVI_SALTY). | 0.940 |
ilvB | ilvN | STM3796 | STM3795 | Valine sensitive; similar to E. coli acetolactate synthase I,valine-sensitive, large subunit (AAC76694.1); Blastp hit to AAC76694.1 (562 aa), 91% identity in aa 1 - 562. | Similar to E. coli acetolactate synthase I, valine sensitive, small subunit (AAC76693.1); Blastp hit to AAC76693.1 (96 aa), 90% identity in aa 1 - 96. | 0.999 |
ilvB | tdcB | STM3796 | STM3244 | Valine sensitive; similar to E. coli acetolactate synthase I,valine-sensitive, large subunit (AAC76694.1); Blastp hit to AAC76694.1 (562 aa), 91% identity in aa 1 - 562. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine to yield pyruv [...] | 0.960 |
ilvB | tdcE | STM3796 | STM3241 | Valine sensitive; similar to E. coli acetolactate synthase I,valine-sensitive, large subunit (AAC76694.1); Blastp hit to AAC76694.1 (562 aa), 91% identity in aa 1 - 562. | Pyruvate formate-lyase 4; Similar to E. coli probable formate acetyltransferase 3 (AAC76149.1); Blastp hit to AAC76149.1 (746 aa), 93% identity in aa 1 - 741; 2-ketobutyrate formate-lyase. | 0.658 |
ilvB | yjgF | STM3796 | STM4458 | Valine sensitive; similar to E. coli acetolactate synthase I,valine-sensitive, large subunit (AAC76694.1); Blastp hit to AAC76694.1 (562 aa), 91% identity in aa 1 - 562. | Putative translation initiation inhibitor; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities and to avoid they are captured by anthranilate phosphoribosyltransferase (TrpD) to generate PRA, an intermediate in the alternative pyrimidine biosynthetic (APB) pathwa [...] | 0.508 |
ilvE | ilvB | STM3903 | STM3796 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. | Valine sensitive; similar to E. coli acetolactate synthase I,valine-sensitive, large subunit (AAC76694.1); Blastp hit to AAC76694.1 (562 aa), 91% identity in aa 1 - 562. | 0.824 |
ilvE | ilvH | STM3903 | STM0117 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | 0.796 |
ilvE | ilvI | STM3903 | STM0116 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. | Acetolactate synthase isozyme III large subunit. (SW:ILVI_SALTY). | 0.706 |
ilvE | ilvN | STM3903 | STM3795 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. | Similar to E. coli acetolactate synthase I, valine sensitive, small subunit (AAC76693.1); Blastp hit to AAC76693.1 (96 aa), 90% identity in aa 1 - 96. | 0.677 |
ilvE | tdcB | STM3903 | STM3244 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine to yield pyruv [...] | 0.985 |
ilvE | tdcE | STM3903 | STM3241 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. | Pyruvate formate-lyase 4; Similar to E. coli probable formate acetyltransferase 3 (AAC76149.1); Blastp hit to AAC76149.1 (746 aa), 93% identity in aa 1 - 741; 2-ketobutyrate formate-lyase. | 0.800 |
ilvE | thrC | STM3903 | STM0004 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. | Similar to E. coli threonine synthase (AAC73115.1); Blastp hit to AAC73115.1 (428 aa), 93% identity in aa 1 - 428. | 0.437 |
ilvE | yjgF | STM3903 | STM4458 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. | Putative translation initiation inhibitor; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities and to avoid they are captured by anthranilate phosphoribosyltransferase (TrpD) to generate PRA, an intermediate in the alternative pyrimidine biosynthetic (APB) pathwa [...] | 0.905 |
ilvH | ilvB | STM0117 | STM3796 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Valine sensitive; similar to E. coli acetolactate synthase I,valine-sensitive, large subunit (AAC76694.1); Blastp hit to AAC76694.1 (562 aa), 91% identity in aa 1 - 562. | 0.999 |
ilvH | ilvE | STM0117 | STM3903 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. | 0.796 |
ilvH | ilvI | STM0117 | STM0116 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Acetolactate synthase isozyme III large subunit. (SW:ILVI_SALTY). | 0.999 |
ilvH | ilvN | STM0117 | STM3795 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Similar to E. coli acetolactate synthase I, valine sensitive, small subunit (AAC76693.1); Blastp hit to AAC76693.1 (96 aa), 90% identity in aa 1 - 96. | 0.971 |
ilvH | tdcB | STM0117 | STM3244 | Acetolactate synthase isozyme III small subunit. (SW:ILVH_SALTY). | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. TdcB also dehydrates serine to yield pyruv [...] | 0.958 |