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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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gatZPutative tagatose 6-phosphate kinase 1; Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of GatY. When expressed alone, GatZ does not show any aldolase activity. Is involved in the catabolism of galactitol. (423 aa)    
Predicted Functional Partners:
gatY
Putative fructose/tagatose biphosphate aldolase; Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is involved in the catabolism of galactitol.
  
 
 0.997
pfkA
6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.964
STM3262
Transcriptional regulator of sugar metabolism; Similar to E. coli split galactitol utilization operon repressor, interrupted (AAC75148.1); Blastp hit to AAC75148.1 (148 aa), 77% identity in aa 1 - 148.
 
  
 0.925
pfkB
Similar to E. coli 6-phosphofructokinase II; suppressor of pfkA (AAC74793.1); Blastp hit to AAC74793.1 (309 aa), 92% identity in aa 1 - 308; Belongs to the carbohydrate kinase PfkB family.
     
 0.922
STM3258
Sugar specific-family of transport protein; similar to E. coli galactitol-specific enzyme IIA of phosphotransferase system (AAC75155.1); Blastp hit to AAC75155.1 (150 aa), 60% identity in aa 1 - 150.
  
  
 0.895
STM3260
Similar to E. coli PTS system galactitol-specific enzyme IIC (AAC75153.1); Blastp hit to AAC75153.1 (451 aa), 85% identity in aa 1 - 446.
 
  
 0.883
STM3259
Similar to E. coli galactitol-specific enzyme IIB of phosphotransferase system (AAC75154.1); Blastp hit to AAC75154.1 (94 aa), 77% identity in aa 1 - 94.
  
  
 0.862
agaR
Aga operon transcriptional repressor; DeoR family; similar to E. coli putative DEOR-type transcriptional regulator of aga operon (AAC76165.1); Blastp hit to AAC76165.1 (269 aa), 26% identity in aa 10 - 252.
     
 0.811
STM3767
Putative cytoplasmic protein.
   
 
  0.802
eda
Multifunctional; similar to E. coli 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase (AAC74920.1); Blastp hit to AAC74920.1 (213 aa), 97% identity in aa 1 - 212; oxaloacetate decarboxylase.
     
  0.800
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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