Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
STM3262Transcriptional regulator of sugar metabolism; Similar to E. coli split galactitol utilization operon repressor, interrupted (AAC75148.1); Blastp hit to AAC75148.1 (148 aa), 77% identity in aa 1 - 148. (257 aa)    
Predicted Functional Partners:
STM3261
Similar to E. coli galactitol-1-phosphate dehydrogenase (AAC75152.1); Blastp hit to AAC75152.1 (346 aa), 68% identity in aa 1 - 344.
  
  
 0.950
gatZ
Putative tagatose 6-phosphate kinase 1; Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of GatY. When expressed alone, GatZ does not show any aldolase activity. Is involved in the catabolism of galactitol.
 
  
 0.925
STM3254
Putative fructose-1-phosphate kinase; Similar to E. coli 6-phosphofructokinase II; suppressor of pfkA (AAC74793.1); Blastp hit to AAC74793.1 (309 aa), 27% identity in aa 4 - 291; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.924
STM2135
Putative inner membrane protein.
      
 0.897
yegQ
Putative protease; Similar to E. coli orf, hypothetical protein (AAC75142.1); Blastp hit to AAC75142.1 (453 aa), 96% identity in aa 1 - 453.
      
 0.854
gatY
Putative fructose/tagatose biphosphate aldolase; Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is involved in the catabolism of galactitol.
  
  
 0.794
STM4442
Putative cytoplasmic protein.
   
  
 0.728
STM0951
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76464.1); Blastp hit to AAC76464.1 (231 aa), 27% identity in aa 52 - 222, 23% identity in aa 101 - 231; Belongs to the pirin family.
      
 0.722
STM0952
Similar to E. coli putative transcriptional regulator LYSR-type (AAC73313.1); Blastp hit to AAC73313.1 (304 aa), 31% identity in aa 1 - 291; Belongs to the LysR transcriptional regulatory family.
      
 0.722
STM1554
Putative coiled-coil protein.
      
 0.673
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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