STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yraNPutative endonuclease; Similar to E. coli orf, hypothetical protein (AAC76182.1); Blastp hit to AAC76182.1 (131 aa), 83% identity in aa 1 - 131; Belongs to the UPF0102 family. (131 aa)    
Predicted Functional Partners:
yraM
Putative transglycosylase; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family.
 
  
 0.967
yraP
Similar to E. coli putative periplasmic protein (AAC76184.1); Blastp hit to AAC76184.1 (191 aa), 92% identity in aa 1 - 191.
    
 0.910
yraO
Putative phosphoheptose isomerase; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily.
 
    0.884
yhcG
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76252.1); Blastp hit to AAC76252.1 (375 aa), 55% identity in aa 115 - 164.
   
  
 0.860
STM4490
Putative Mrr restriction endonuclease.
      
 0.855
sfsA
Regulator for maltose metabolism; Binds to DNA non-specifically. Could be a regulatory factor involved in maltose metabolism.
      
 0.746
yhgH
Putative amidophosphoribosyltransferase; Could be involved in gluconate metabolism.
 
    0.742
yifB
Putative magnesium chelatase, subunit ChlI; Hypothetical 55.0 Kda protein in pssR-ilLl intergenic region. (SW:YIFB_SALTY); Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.
 
  
 0.720
smf
Putative protein involved in DNA uptake; Similar to E. coli orf, fragment 1 (AAC76311.1); Blastp hit to AAC76311.1 (253 aa), 66% identity in aa 1 - 248.
 
  
 0.699
mrr
Similar to E. coli restriction of methylated adenine (AAC77307.1); Blastp hit to AAC77307.1 (304 aa), 77% identity in aa 1 - 304.
   
  
 0.672
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.