STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yraPSimilar to E. coli putative periplasmic protein (AAC76184.1); Blastp hit to AAC76184.1 (191 aa), 92% identity in aa 1 - 191. (191 aa)    
Predicted Functional Partners:
yraO
Putative phosphoheptose isomerase; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily.
 
    0.949
yraM
Putative transglycosylase; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family.
 
    0.947
yraN
Putative endonuclease; Similar to E. coli orf, hypothetical protein (AAC76182.1); Blastp hit to AAC76182.1 (131 aa), 83% identity in aa 1 - 131; Belongs to the UPF0102 family.
    
 0.910
yfgL
Putative serine/threonine protein kinase; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.748
yjbJ
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77015.1); Blastp hit to AAC77015.1 (69 aa), 95% identity in aa 1 - 69; Belongs to the UPF0337 (CsbD) family.
 
    0.710
yfiO
Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.
  
  
 0.687
yaeT
Putative outer membrane antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
  
  
 0.670
fkpA
Similar to E. coli FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (AAC76372.1); Blastp hit to AAC76372.1 (270 aa), 90% identity in aa 1 - 270.
   
  
 0.656
yicJ
Putative GPH family transport protein; Similar to E. coli putative permease (AAC76681.1); Blastp hit to AAC76681.1 (479 aa), 91% identity in aa 20 - 479.
      
 0.649
yraL
Putative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.646
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.