| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| nlpB | nlpI | STM2488 | STM3281 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | 0.749 |
| nlpB | ompA | STM2488 | STM1070 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative membrane component hydrogenase; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. | 0.808 |
| nlpB | proQ | STM2488 | STM1846 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Activator of proP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.834 |
| nlpB | yjgD | STM2488 | STM4470 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative cytoplasmic protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.672 |
| nlpB | yrbK | STM2488 | STM3317 | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Putative inner membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.782 |
| nlpI | nlpB | STM3281 | STM2488 | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.749 |
| nlpI | ompA | STM3281 | STM1070 | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | Putative membrane component hydrogenase; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. | 0.779 |
| nlpI | pnp | STM3281 | STM3282 | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. Is a global regulator of virulence and persistency. | 0.841 |
| nlpI | prc | STM3281 | STM1845 | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | Carboxy-terminal protease for penicillin-binding protein 3; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses (By similarity). | 0.943 |
| nlpI | proQ | STM3281 | STM1846 | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | Activator of proP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.798 |
| nlpI | spr | STM3281 | STM2214 | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | Putative lipoprotein; Suppresses thermosensitivity of prc mutants at low osmolality; similar to E. coli putative lipoprotein (AAC75236.1); Blastp hit to AAC75236.1 (188 aa), 92% identity in aa 1 - 188. | 0.799 |
| nlpI | tolR | STM3281 | STM0746 | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | Tol protein, role in outer membrane integrity; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.858 |
| nlpI | yibP | STM3281 | STM3705 | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | Similar to E. coli putative membrane protein (AAC76637.1); Blastp hit to AAC76637.1 (427 aa), 91% identity in aa 1 - 427. | 0.759 |
| nlpI | yjgD | STM3281 | STM4470 | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | Putative cytoplasmic protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.779 |
| nlpI | yrbK | STM3281 | STM3317 | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | Putative inner membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.777 |
| ompA | nlpB | STM1070 | STM2488 | Putative membrane component hydrogenase; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. | Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.808 |
| ompA | nlpI | STM1070 | STM3281 | Putative membrane component hydrogenase; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | 0.779 |
| ompA | proQ | STM1070 | STM1846 | Putative membrane component hydrogenase; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. | Activator of proP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.415 |
| ompA | tolR | STM1070 | STM0746 | Putative membrane component hydrogenase; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. | Tol protein, role in outer membrane integrity; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. | 0.823 |
| pnp | nlpI | STM3282 | STM3281 | Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. Is a global regulator of virulence and persistency. | Lipoprotein, cell division; May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity). | 0.841 |
