| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| guaA | infB | STM2510 | STM3286 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Protein chain initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). | 0.678 |
| guaA | nusA | STM2510 | STM3287 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | L factor; Participates in both transcription termination and antitermination. | 0.526 |
| guaA | pnp | STM2510 | STM3282 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. Is a global regulator of virulence and persistency. | 0.737 |
| guaA | ribF | STM2510 | STM0045 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Flavokinase and FAD synthetase; Similar to E. coli putative regulator (AAC73136.1); Blastp hit to AAC73136.1 (313 aa), 89% identity in aa 1 - 309; Belongs to the ribF family. | 0.498 |
| guaA | rpsO | STM2510 | STM3283 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.673 |
| guaA | truB | STM2510 | STM3284 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | tRNA pseudouridine 5S synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.929 |
| guaA | yggH | STM2510 | STM3109 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Putative S-adenosylmethionine-dependent methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.427 |
| guaA | yjbN | STM2510 | STM4243 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Putative TIM-barrel enzyme; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | 0.474 |
| infB | guaA | STM3286 | STM2510 | Protein chain initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.678 |
| infB | nusA | STM3286 | STM3287 | Protein chain initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). | L factor; Participates in both transcription termination and antitermination. | 0.998 |
| infB | pnp | STM3286 | STM3282 | Protein chain initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). | Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. Is a global regulator of virulence and persistency. | 0.973 |
| infB | rbfA | STM3286 | STM3285 | Protein chain initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). | Ribosome-binding factor; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.996 |
| infB | rpsO | STM3286 | STM3283 | Protein chain initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.940 |
| infB | truA | STM3286 | STM2368 | Protein chain initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). | Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.479 |
| infB | truB | STM3286 | STM3284 | Protein chain initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). | tRNA pseudouridine 5S synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.994 |
| nusA | guaA | STM3287 | STM2510 | L factor; Participates in both transcription termination and antitermination. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.526 |
| nusA | infB | STM3287 | STM3286 | L factor; Participates in both transcription termination and antitermination. | Protein chain initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). | 0.998 |
| nusA | pnp | STM3287 | STM3282 | L factor; Participates in both transcription termination and antitermination. | Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. Is a global regulator of virulence and persistency. | 0.967 |
| nusA | rbfA | STM3287 | STM3285 | L factor; Participates in both transcription termination and antitermination. | Ribosome-binding factor; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.754 |
| nusA | rpsO | STM3287 | STM3283 | L factor; Participates in both transcription termination and antitermination. | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.764 |
STRING v12.5 is now available!
