Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
argGSimilar to E. coli argininosuccinate synthetase (AAC76205.1); Blastp hit to AAC76205.1 (447 aa), 96% identity in aa 1 - 447; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (469 aa)    
Predicted Functional Partners:
argH
Similar to E. coli argininosuccinate lyase (AAC76942.1); Blastp hit to AAC76942.1 (457 aa), 94% identity in aa 1 - 456.
 
 0.999
arcB-2
Putative ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.996
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.
 
  
 0.995
argE
Acetylornithine deacetylase; Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde.
  
 0.993
argI
Ornithine carbamoyltransferase 1; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 
 0.990
argA
N-alpha-acetylglutamate synthase; Amino-acid acetyltransferase; similar to E. coli N-acetylglutamate synthase; amino acid acetyltransferase (AAC75857.1); Blastp hit to AAC75857.1 (443 aa), 93% identity in aa 1 - 443; Belongs to the acetyltransferase family. ArgA subfamily.
 
  
 0.985
carB
Carbamoyl-phosphate synthase large chain. (SW:CARB_SALTY).
 
 
 0.983
argC
N-acetyl-gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.979
arcA-2
Putative arginine deiminase.
     
 0.944
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.933
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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