| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| emrR | nadR | STM2813 | STM4580 | Transcriptional repressor of emrAB operon; MarR family; similar to E. coli regulator of plasmid mcrB operon (microcin B17 synthesis) (AAC75731.1); Blastp hit to AAC75731.1 (176 aa), 93% identity in aa 1 - 175. | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | 0.429 |
| emrR | nlp | STM2813 | STM3306 | Transcriptional repressor of emrAB operon; MarR family; similar to E. coli regulator of plasmid mcrB operon (microcin B17 synthesis) (AAC75731.1); Blastp hit to AAC75731.1 (176 aa), 93% identity in aa 1 - 175. | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | 0.484 |
| emrR | yajG | STM2813 | STM0445 | Transcriptional repressor of emrAB operon; MarR family; similar to E. coli regulator of plasmid mcrB operon (microcin B17 synthesis) (AAC75731.1); Blastp hit to AAC75731.1 (176 aa), 93% identity in aa 1 - 175. | Similar to E. coli putative polymerase/proteinase (AAC73537.1); Blastp hit to AAC73537.1 (226 aa), 85% identity in aa 20 - 226. | 0.603 |
| nadR | emrR | STM4580 | STM2813 | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | Transcriptional repressor of emrAB operon; MarR family; similar to E. coli regulator of plasmid mcrB operon (microcin B17 synthesis) (AAC75731.1); Blastp hit to AAC75731.1 (176 aa), 93% identity in aa 1 - 175. | 0.429 |
| nadR | nlp | STM4580 | STM3306 | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | 0.464 |
| nadR | pgpB | STM4580 | STM1710 | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | Similar to E. coli non-essential phosphatidylglycerophosphate phosphatase, membrane bound (AAC74360.1); Blastp hit to AAC74360.1 (254 aa), 82% identity in aa 1 - 254. | 0.781 |
| nadR | yhbP | STM4580 | STM3270 | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76188.1); Blastp hit to AAC76188.1 (147 aa), 83% identity in aa 1 - 147; Belongs to the UPF0306 family. | 0.493 |
| nlp | emrR | STM3306 | STM2813 | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | Transcriptional repressor of emrAB operon; MarR family; similar to E. coli regulator of plasmid mcrB operon (microcin B17 synthesis) (AAC75731.1); Blastp hit to AAC75731.1 (176 aa), 93% identity in aa 1 - 175. | 0.484 |
| nlp | nadR | STM3306 | STM4580 | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | 0.464 |
| nlp | pagP | STM3306 | STM0628 | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | PhoPQ-activated gene; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. Required for resistance to cationic antimicrobial peptides (CAMPs). Modifications of lipid A with a palmitate chain allow to evade host immune defenses by resisting antimicrobial peptides and attenuating the inflammatory response to infection triggered by lipopolysaccharide through the Toll-like receptor 4 (TLR4) signal transduction pathway. | 0.594 |
| nlp | pgpB | STM3306 | STM1710 | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | Similar to E. coli non-essential phosphatidylglycerophosphate phosphatase, membrane bound (AAC74360.1); Blastp hit to AAC74360.1 (254 aa), 82% identity in aa 1 - 254. | 0.461 |
| nlp | pstS | STM3306 | STM3857 | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | High-affinity phosphate transporter; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. | 0.697 |
| nlp | yajG | STM3306 | STM0445 | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | Similar to E. coli putative polymerase/proteinase (AAC73537.1); Blastp hit to AAC73537.1 (226 aa), 85% identity in aa 20 - 226. | 0.543 |
| nlp | ycfM | STM3306 | STM1207 | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | Putative outer membrane lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). | 0.467 |
| nlp | yhbP | STM3306 | STM3270 | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76188.1); Blastp hit to AAC76188.1 (147 aa), 83% identity in aa 1 - 147; Belongs to the UPF0306 family. | 0.605 |
| nlp | yifE | STM3306 | STM3898 | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | Putative LysR type transcriptional regulator with pssR; Similar to E. coli orf, hypothetical protein (AAC77485.1); Blastp hit to AAC77485.1 (112 aa), 95% identity in aa 1 - 112; Belongs to the UPF0438 family. | 0.446 |
| nlp | ynbE | STM3306 | STM1645 | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | Putative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC74464.1); Blastp hit to AAC74464.1 (61 aa), 73% identity in aa 1 - 61. | 0.437 |
| pagP | nlp | STM0628 | STM3306 | PhoPQ-activated gene; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. Required for resistance to cationic antimicrobial peptides (CAMPs). Modifications of lipid A with a palmitate chain allow to evade host immune defenses by resisting antimicrobial peptides and attenuating the inflammatory response to infection triggered by lipopolysaccharide through the Toll-like receptor 4 (TLR4) signal transduction pathway. | Regulatory factor of maltose metabolism; Similar to Ner repressor protein of phage Mu; similar to E. coli regulatory factor of maltose metabolism; similar to Ner repressor protein of phage Mu (AAC76220.1); Blastp hit to AAC76220.1 (92 aa), 86% identity in aa 1 - 92. | 0.594 |
| pagP | yajG | STM0628 | STM0445 | PhoPQ-activated gene; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. Required for resistance to cationic antimicrobial peptides (CAMPs). Modifications of lipid A with a palmitate chain allow to evade host immune defenses by resisting antimicrobial peptides and attenuating the inflammatory response to infection triggered by lipopolysaccharide through the Toll-like receptor 4 (TLR4) signal transduction pathway. | Similar to E. coli putative polymerase/proteinase (AAC73537.1); Blastp hit to AAC73537.1 (226 aa), 85% identity in aa 20 - 226. | 0.426 |
| pgpB | nadR | STM1710 | STM4580 | Similar to E. coli non-essential phosphatidylglycerophosphate phosphatase, membrane bound (AAC74360.1); Blastp hit to AAC74360.1 (254 aa), 82% identity in aa 1 - 254. | Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...] | 0.781 |