STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhcQPutative membrane located multidrug resistance protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (310 aa)    
Predicted Functional Partners:
yhcP
Putative inner membrane protein; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
 
 0.999
yhcR
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76274.1); Blastp hit to AAC76274.1 (90 aa), 98% identity in aa 24 - 90.
  
    0.860
STM0347
Putative response regulator; Unknown (gi|6707275).
      
 0.839
yeeZ
Similar to E. coli putative enzyme of sugar metabolism (AAC75077.1); Blastp hit to AAC75077.1 (274 aa), 89% identity in aa 1 - 274.
      
 0.837
ybjZ
Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.818
ydhC
Similar to E. coli putative transport protein (AAC74732.1); Blastp hit to AAC74732.1 (403 aa), 85% identity in aa 1 - 403.
   
 
 0.767
ydeD
Putative permease, integral membrane protein; May be an export pump for several amino acids and their metabolites, including cysteine; Belongs to the EamA transporter family.
      
 0.764
ydfJ
Similar to E. coli putative transport protein (AAC74616.1); Blastp hit to AAC74616.1 (427 aa), 86% identity in aa 1 - 293.
      
 0.725
emrB
Putative MFS superfamily multidrug transport protein; Similar to E. coli multidrug resistance; probably membrane translocase (AAC75733.1); Blastp hit to AAC75733.1 (512 aa), 95% identity in aa 1 - 512; Belongs to the major facilitator superfamily.
  
 
 0.676
ydhK
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74717.1); Blastp hit to AAC74717.1 (670 aa), 84% identity in aa 1 - 669.
  
 0.615
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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