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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhcRPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76274.1); Blastp hit to AAC76274.1 (90 aa), 98% identity in aa 24 - 90. (67 aa)    
Predicted Functional Partners:
yhcQ
Putative membrane located multidrug resistance protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
    0.860
yhcP
Putative inner membrane protein; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
  
    0.827
endA
Similar to E. coli DNA-specific endonuclease I (AAC75982.1); Blastp hit to AAC75982.1 (235 aa), 87% identity in aa 1 - 235.
      
 0.763
yhiI
Similar to E. coli putative membrane protein (AAC76512.1); Blastp hit to AAC76512.1 (355 aa), 87% identity in aa 1 - 355.
   
  
 0.722
yhcS
Similar to E. coli putative transcriptional regulator LYSR-type (AAC76275.1); Blastp hit to AAC76275.1 (309 aa), 95% identity in aa 1 - 309; Belongs to the LysR transcriptional regulatory family.
     
 0.583
ushA
UDP-sugar hydrolase 5'-nucleotidase; Silent protein USHA(0) precursor. (SW:USHA_SALTY); Belongs to the 5'-nucleotidase family.
   
  
 0.580
ydgF
Putative membrane transporter of cations and cationic drugs; Catalyzes the excretion of spermidine.
      
 0.577
yhcO
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76271.1); Blastp hit to AAC76271.1 (90 aa), 76% identity in aa 1 - 90.
       0.470
yfaZ
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75310.1); Blastp hit to AAC75310.1 (187 aa), 86% identity in aa 8 - 187.
      
 0.452
kdgR
Putative IclR family transcriptional repressor; Similar to E. coli putative regulator (AAC74897.1); Blastp hit to AAC74897.1 (263 aa), 96% identity in aa 1 - 263.
      
 0.450
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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