Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yhdPPutative protease; Similar to E. coli orf, hypothetical protein (AAC76277.1); Blastp hit to AAC76277.1 (986 aa), 80% identity in aa 1 - 986. (1266 aa)    
Predicted Functional Partners:
ydbH
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74463.1); Blastp hit to AAC74463.1 (879 aa), 78% identity in aa 1 - 878.
  
  
 0.955
mreD
Rod shape-determining protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
    0.920
yhjG
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76549.1); Blastp hit to AAC76549.1 (691 aa), 93% identity in aa 6 - 691.
     
 0.897
yicH
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76679.1); Blastp hit to AAC76679.1 (569 aa), 80% identity in aa 1 - 567.
     
 0.897
ynbE
Putative outer membrane lipoprotein; Similar to E. coli orf, hypothetical protein (AAC74464.1); Blastp hit to AAC74464.1 (61 aa), 73% identity in aa 1 - 61.
      
 0.858
yhdE
Putative inhibitor of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
    0.851
tldD
Similar to E. coli suppresses inhibitory activity of CsrA (AAC76276.1); Blastp hit to AAC76276.1 (481 aa), 94% identity in aa 1 - 481.
  
  
 0.850
asmA
Similar to E. coli suppressor of ompF assembly mutants (AAC75125.1); Blastp hit to AAC75125.1 (617 aa), 76% identity in aa 1 - 617.
 
  
 0.792
hnr
Response regulator in protein turnover; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.
  
     0.767
ydbL
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74465.1); Blastp hit to AAC74465.1 (110 aa), 70% identity in aa 3 - 109.
      
 0.764
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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