node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acrF | envR | STM3391 | STM3389 | RND family multidrug transport protein; Similar to E. coli integral transmembrane protein; acridine resistance (AAC76298.1); Blastp hit to AAC76298.1 (1034 aa), 22% identity in aa 1 - 506; acriflavin resistance protein F. | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | 0.575 |
acrF | ybjZ | STM3391 | STM0942 | RND family multidrug transport protein; Similar to E. coli integral transmembrane protein; acridine resistance (AAC76298.1); Blastp hit to AAC76298.1 (1034 aa), 22% identity in aa 1 - 506; acriflavin resistance protein F. | Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.899 |
acrF | yegN | STM3391 | STM2127 | RND family multidrug transport protein; Similar to E. coli integral transmembrane protein; acridine resistance (AAC76298.1); Blastp hit to AAC76298.1 (1034 aa), 22% identity in aa 1 - 506; acriflavin resistance protein F. | Putative outer membrane receptor; Similar to E. coli orf, hypothetical protein (AAC75136.1); Blastp hit to AAC75136.1 (1040 aa), 91% identity in aa 1 - 1040; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily. | 0.418 |
bglJ | envR | STM4548 | STM3389 | Transcriptional regulator (activator) of bgl operon; LuxR/UhpA family; similar to E. coli 2-component transcriptional regulator (AAC77322.1); Blastp hit to AAC77322.1 (225 aa), 63% identity in aa 1 - 223. | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | 0.417 |
envR | acrF | STM3389 | STM3391 | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | RND family multidrug transport protein; Similar to E. coli integral transmembrane protein; acridine resistance (AAC76298.1); Blastp hit to AAC76298.1 (1034 aa), 22% identity in aa 1 - 506; acriflavin resistance protein F. | 0.575 |
envR | bglJ | STM3389 | STM4548 | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | Transcriptional regulator (activator) of bgl operon; LuxR/UhpA family; similar to E. coli 2-component transcriptional regulator (AAC77322.1); Blastp hit to AAC77322.1 (225 aa), 63% identity in aa 1 - 223. | 0.417 |
envR | rhuM | STM3389 | STM3755 | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | Putative cytoplasmic protein; Pathogenicity island encoded protein: SPI3; RhuM (gi|4324608). | 0.459 |
envR | stjB | STM3389 | STM4572 | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | Similar to E. coli putative outer membrane protein (AAC76248.1); Blastp hit to AAC76248.1 (793 aa), 40% identity in aa 29 - 793. | 0.565 |
envR | ybjZ | STM3389 | STM0942 | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.404 |
envR | ycfQ | STM3389 | STM1213 | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | Putative transcriptional repressor (TetR/AcrR family); Similar to E. coli orf, hypothetical protein (AAC74195.1); Blastp hit to AAC74195.1 (236 aa), 80% identity in aa 27 - 236. | 0.459 |
envR | yegN | STM3389 | STM2127 | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | Putative outer membrane receptor; Similar to E. coli orf, hypothetical protein (AAC75136.1); Blastp hit to AAC75136.1 (1040 aa), 91% identity in aa 1 - 1040; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily. | 0.452 |
envR | yjdC | STM3389 | STM4322 | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | Putative merR family bacterial regulatory protein; Similar to E. coli orf, hypothetical protein (AAC77095.1); Blastp hit to AAC77095.1 (199 aa), 88% identity in aa 9 - 199. | 0.710 |
rhuM | envR | STM3755 | STM3389 | Putative cytoplasmic protein; Pathogenicity island encoded protein: SPI3; RhuM (gi|4324608). | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | 0.459 |
rhuM | stjB | STM3755 | STM4572 | Putative cytoplasmic protein; Pathogenicity island encoded protein: SPI3; RhuM (gi|4324608). | Similar to E. coli putative outer membrane protein (AAC76248.1); Blastp hit to AAC76248.1 (793 aa), 40% identity in aa 29 - 793. | 0.574 |
stjB | envR | STM4572 | STM3389 | Similar to E. coli putative outer membrane protein (AAC76248.1); Blastp hit to AAC76248.1 (793 aa), 40% identity in aa 29 - 793. | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | 0.565 |
stjB | rhuM | STM4572 | STM3755 | Similar to E. coli putative outer membrane protein (AAC76248.1); Blastp hit to AAC76248.1 (793 aa), 40% identity in aa 29 - 793. | Putative cytoplasmic protein; Pathogenicity island encoded protein: SPI3; RhuM (gi|4324608). | 0.574 |
ybjZ | acrF | STM0942 | STM3391 | Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | RND family multidrug transport protein; Similar to E. coli integral transmembrane protein; acridine resistance (AAC76298.1); Blastp hit to AAC76298.1 (1034 aa), 22% identity in aa 1 - 506; acriflavin resistance protein F. | 0.899 |
ybjZ | envR | STM0942 | STM3389 | Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | 0.404 |
ybjZ | yegN | STM0942 | STM2127 | Putative ABC superfamily (atp&memb) transport protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Putative outer membrane receptor; Similar to E. coli orf, hypothetical protein (AAC75136.1); Blastp hit to AAC75136.1 (1040 aa), 91% identity in aa 1 - 1040; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily. | 0.707 |
ycfQ | envR | STM1213 | STM3389 | Putative transcriptional repressor (TetR/AcrR family); Similar to E. coli orf, hypothetical protein (AAC74195.1); Blastp hit to AAC74195.1 (236 aa), 80% identity in aa 27 - 236. | Transcriptional repressor for envCD (acrEF); TetR/AcrR family; similar to E. coli putative transcriptional regulator (AAC76296.1); Blastp hit to AAC76296.1 (220 aa), 68% identity in aa 1 - 211. | 0.459 |