STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smgPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76309.1); Blastp hit to AAC76309.1 (157 aa), 94% identity in aa 1 - 157; Belongs to the Smg family. (157 aa)    
Predicted Functional Partners:
smf
Putative protein involved in DNA uptake; Similar to E. coli orf, fragment 1 (AAC76311.1); Blastp hit to AAC76311.1 (253 aa), 66% identity in aa 1 - 248.
 
  
 0.916
ppdB
Prepilin peptidase dependent protein B; Putative component in type IV pilin biogenesis; similar to E. coli prepilin peptidase dependent protein B (AAC75864.1); Blastp hit to AAC75864.1 (187 aa), 67% identity in aa 3 - 187.
      
 0.815
yrdD
Similar to E. coli putative DNA topoisomerase (AAC76308.1); Blastp hit to AAC76308.1 (169 aa), 33% identity in aa 3 - 157.
 
  
 0.801
yafV
Similar to E. coli putative EC 3.5. amidase-type enzyme (AAC73323.1); Blastp hit to AAC73323.1 (256 aa), 82% identity in aa 3 - 255.
   
  
 0.768
aroE
Dehydroshikimate reductase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.767
yrdB
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76305.1); Blastp hit to AAC76305.1 (85 aa), 71% identity in aa 1 - 84.
  
    0.765
yrdC
Putative translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
       0.763
ybeL
Similar to E. coli putative alpha helical protein (AAC73744.1); Blastp hit to AAC73744.1 (160 aa), 91% identity in aa 1 - 160.
  
    0.746
yacF
Putative cytoplasmic protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
  
     0.745
yfeD
Putative negative regulator; Similar to E. coli orf, hypothetical protein (AAC75456.1); Blastp hit to AAC75456.1 (130 aa), 70% identity in aa 1 - 129.
      
 0.740
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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