| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aefA | trkA | STM0478 | STM3409 | Putative small-conductance mechanosensitive channel; Similar to E. coli putative alpha helix protein (AAC73567.1); Blastp hit to AAC73567.1 (1120 aa), 89% identity in aa 1 - 1117. | Trk system transport of potassium protein; Part of the constitutive potassium transport systems TrkG and TrkH. May regulate the transport activity of TrkG and TrkH systems. Binds to NAD(+) and NADH. In Salmonella it is required for resistance to antimicrobial peptides. | 0.680 |
| def | fmt | STM3406 | STM3407 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus. | 0.998 |
| def | mscL | STM3406 | STM3410 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.428 |
| def | nifJ | STM3406 | STM1651 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | 0.756 |
| def | sun | STM3406 | STM3408 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Putative rRNA methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.741 |
| def | trkA | STM3406 | STM3409 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Trk system transport of potassium protein; Part of the constitutive potassium transport systems TrkG and TrkH. May regulate the transport activity of TrkG and TrkH systems. Binds to NAD(+) and NADH. In Salmonella it is required for resistance to antimicrobial peptides. | 0.701 |
| fmt | def | STM3407 | STM3406 | 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.998 |
| fmt | mscL | STM3407 | STM3410 | 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus. | Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.486 |
| fmt | nifJ | STM3407 | STM1651 | 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus. | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | 0.422 |
| fmt | sun | STM3407 | STM3408 | 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus. | Putative rRNA methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.985 |
| fmt | trkA | STM3407 | STM3409 | 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus. | Trk system transport of potassium protein; Part of the constitutive potassium transport systems TrkG and TrkH. May regulate the transport activity of TrkG and TrkH systems. Binds to NAD(+) and NADH. In Salmonella it is required for resistance to antimicrobial peptides. | 0.949 |
| himA | sun | STM1339 | STM3408 | Integration host factor (IHF), alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. | Putative rRNA methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.481 |
| himA | trkA | STM1339 | STM3409 | Integration host factor (IHF), alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. | Trk system transport of potassium protein; Part of the constitutive potassium transport systems TrkG and TrkH. May regulate the transport activity of TrkG and TrkH systems. Binds to NAD(+) and NADH. In Salmonella it is required for resistance to antimicrobial peptides. | 0.721 |
| kdpD | nifJ | STM0703 | STM1651 | Sensory kinase in two-component regulatory system wtih KdpE; Regulates kdp operon (high-affinity potassium transport system); similar to E. coli sensor for high-affinity potassium transport system (AAC73789.1); Blastp hit to AAC73789.1 (894 aa), 89% identity in aa 1 - 894. | Similar to E. coli putative oxidoreductase, Fe-S subunit (AAC74460.1); Blastp hit to AAC74460.1 (1174 aa), 92% identity in aa 1 - 1174. | 0.502 |
| kdpD | trkA | STM0703 | STM3409 | Sensory kinase in two-component regulatory system wtih KdpE; Regulates kdp operon (high-affinity potassium transport system); similar to E. coli sensor for high-affinity potassium transport system (AAC73789.1); Blastp hit to AAC73789.1 (894 aa), 89% identity in aa 1 - 894. | Trk system transport of potassium protein; Part of the constitutive potassium transport systems TrkG and TrkH. May regulate the transport activity of TrkG and TrkH systems. Binds to NAD(+) and NADH. In Salmonella it is required for resistance to antimicrobial peptides. | 0.792 |
| kdpD | trkH | STM0703 | STM3986 | Sensory kinase in two-component regulatory system wtih KdpE; Regulates kdp operon (high-affinity potassium transport system); similar to E. coli sensor for high-affinity potassium transport system (AAC73789.1); Blastp hit to AAC73789.1 (894 aa), 89% identity in aa 1 - 894. | Trk family potassium transport protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA and requires TrkE for transport activity (By similarity); Belongs to the TrkH potassium transport family. | 0.805 |
| mscL | def | STM3410 | STM3406 | Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.428 |
| mscL | fmt | STM3410 | STM3407 | Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus. | 0.486 |
| mscL | sun | STM3410 | STM3408 | Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Putative rRNA methylase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.569 |
| mscL | trkA | STM3410 | STM3409 | Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Trk system transport of potassium protein; Part of the constitutive potassium transport systems TrkG and TrkH. May regulate the transport activity of TrkG and TrkH systems. Binds to NAD(+) and NADH. In Salmonella it is required for resistance to antimicrobial peptides. | 0.716 |
