STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yheOPutative regulator; Similar to E. coli orf, hypothetical protein (AAC76371.1); Blastp hit to AAC76371.1 (244 aa), 97% identity in aa 5 - 244. (240 aa)    
Predicted Functional Partners:
yheL
Putative oxidation of intracellular sulfur; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
  
  
 0.903
yheN
Putative ACR involved in intracellular sulfur reduction; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.
  
    0.834
yheM
Putative oxidation of intracellular sulfur; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
  
    0.813
yecM
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74945.1); Blastp hit to AAC74945.1 (190 aa), 84% identity in aa 3 - 190.
  
     0.681
rpsL
30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.
  
    0.625
pqaB
Putative melittin resistance protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.
      
 0.575
yjgF
Putative translation initiation inhibitor; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities and to avoid they are captured by anthranilate phosphoribosyltransferase (TrpD) to generate PRA, an intermediate in the alternative pyrimidine biosynthetic (APB) pathwa [...]
  
  
 0.486
yafA
Putative hydrolase of the alpha/beta superfamily; Displays esterase activity toward pNP-butyrate.
  
     0.484
yggL
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75996.1); Blastp hit to AAC75996.1 (118 aa), 95% identity in aa 11 - 118.
  
     0.480
yafD
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73314.1); Blastp hit to AAC73314.1 (266 aa), 96% identity in aa 8 - 266.
  
    0.476
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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