Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yheTContains alpha/beta-hydrolase fold; similar to E. coli orf, hypothetical protein (AAC76378.1); Blastp hit to AAC76378.1 (340 aa), 84% identity in aa 1 - 339. (355 aa)    
Predicted Functional Partners:
yheU
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76379.1); Blastp hit to AAC76379.1 (72 aa), 89% identity in aa 8 - 72.
       0.773
xapA
Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
      
 0.678
prkB
Similar to E. coli probable phosphoribulokinase (AAC76380.1); Blastp hit to AAC76380.1 (289 aa), 97% identity in aa 1 - 289.
  
    0.649
idnR
L-idonate regulator; GalR/LacI family; similar to E. coli L-idonate transcriptional regulator (AAC77221.1); Blastp hit to AAC77221.1 (332 aa), 89% identity in aa 1 - 332.
      
 0.616
STM3461
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74737.1); Blastp hit to AAC74737.1 (101 aa), 65% identity in aa 3 - 100.
  
    0.506
yhdP
Putative protease; Similar to E. coli orf, hypothetical protein (AAC76277.1); Blastp hit to AAC76277.1 (986 aa), 80% identity in aa 1 - 986.
 
     0.410
kefB
CPA2 family K+:H+ antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
 
     0.405
kefC
CPA2 family K+ efflux antiporter, glutathione-regulated; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
 
     0.404
STM1528
Putative outer membrane protein.
  
    0.401
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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