STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhfKPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76383.1); Blastp hit to AAC76383.1 (696 aa), 86% identity in aa 1 - 695. (695 aa)    
Predicted Functional Partners:
yhfA
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76381.1); Blastp hit to AAC76381.1 (134 aa), 94% identity in aa 1 - 134.
  
  
 0.919
crp
Catabolite activator protein (CAP); A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding to regulate transcription. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP. Plays a major role in carbon catabolite repression (CCR) (By similarity).
  
  
 0.771
ycdY
Similar to E. coli putative oxidoreductase component (AAC74119.1); Blastp hit to AAC74119.1 (184 aa), 86% identity in aa 1 - 184.
  
     0.760
ampE
Putative transmembrane protein; Similar to E. coli regulates ampC (AAC73222.1); Blastp hit to AAC73222.1 (284 aa), 84% identity in aa 1 - 284.
  
     0.758
yeeA
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75069.1); Blastp hit to AAC75069.1 (352 aa), 79% identity in aa 1 - 352.
 
     0.739
ybhL
Putative permease; Similar to E. coli orf, hypothetical protein (AAC73873.1); Blastp hit to AAC73873.1 (234 aa), 87% identity in aa 1 - 234; Belongs to the BI1 family.
      
 0.726
ygjQ
Putative integral membrane protein; Similar to E. coli orf, hypothetical protein (AAC76121.1); Blastp hit to AAC76121.1 (230 aa), 73% identity in aa 1 - 230.
      
 0.726
ydgM
Putative alternative beta subunit of Na+-transporting NADH:ubiquinone oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
   
  
 0.678
yajO
Putative oxidoreductase / K + channel protein; Similar to E. coli putative NAD(P)H-dependent xylose reductase (AAC73522.1); Blastp hit to AAC73522.1 (348 aa), 92% identity in aa 25 - 348.
      
 0.673
yhjJ
Putative Zn-dependent peptidase; Protein YHJJ precursor. (SW:YHJJ_SALTY); Belongs to the peptidase M16 family.
  
    0.660
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (64%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.