Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yhfGPutative cytoplasmic protein; Hypothetical 6.8 Kda protein in fic-ppiA intergenic region. (SW:YHFG_SALTY). (55 aa)    
Predicted Functional Partners:
fic
Putative cell filamentation protein; Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (By similarity). Involved in cell filamentation induced by cyclic AMP.
  
 
 0.960
ydcZ
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74529.1); Blastp hit to AAC74529.1 (149 aa), 86% identity in aa 1 - 149.
      
 0.897
STM2779
Putative inner membrane protein.
      
 0.852
STM0341
Putative inner membrane protein.
      
 0.726
pabA
P-aminobenzoate synthetase component II; Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p- aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB (By similarity).
       0.718
argD
Acetylornithine transaminase; Involved in both the arginine and lysine biosynthetic pathways.
  
    0.691
ycgB
Similar to E. coli putative sporulation protein (AAC74272.1); Blastp hit to AAC74272.1 (510 aa), 96% identity in aa 1 - 510.
   
    0.684
yjhX
Putative cytoplasmic protein; Belongs to the UPF0386 family.
      
 0.645
ppiA
Peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
       0.546
uspB
Universal stress protein B; Involved in stationary-phase resistance to ethanol; similar to E. coli orf, hypothetical protein (AAC76519.1); Blastp hit to AAC76519.1 (111 aa), 95% identity in aa 1 - 111.
   
    0.514
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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