STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nirCFNT family nitrite transport protein; Catalyzes nitrite uptake and nitrite export across the cytoplasmic membrane; Belongs to the FNT transporter (TC 2.A.44) family. (269 aa)    
Predicted Functional Partners:
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 0.973
nirD
Nitrite reductase small subunit; Required for activity of the reductase.
 
  
 0.953
nirB
Similar to E. coli nitrite reductase (NAD(P)H) subunit (AAC76390.1); Blastp hit to AAC76390.1 (847 aa), 95% identity in aa 1 - 847; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.943
narK
Similar to E. coli nitrite extrusion protein (AAC74307.1); Blastp hit to AAC74307.1 (463 aa), 94% identity in aa 1 - 462.
  
  
 0.772
yfdC
Similar to E. coli putative transport (AAC75407.1); Blastp hit to AAC75407.1 (310 aa), 87% identity in aa 1 - 304.
      
 0.697
nrfE
Formate-dependent nitrite reductase; Possible subunit of a heme lyase.
   
  
 0.660
yadF
Putative carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
    0.644
nrfA
Nitrite reductase periplasmic cytochrome c(552); Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.
   
  
 0.602
ygbD
Putative oxidoreductase; One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase.
  
   
 0.601
narG
Similar to E. coli nitrate reductase 1, alpha subunit (AAC74308.1); Blastp hit to AAC74308.1 (1247 aa), 95% identity in aa 1 - 1247; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
  
 0.595
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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