Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
bigAPutative surface-exposed virulence protein BigA (gi|5081595). (1953 aa)    
Predicted Functional Partners:
STM1009
Gifsy-2 prophage exodeoxyribonuclease; Exodeoxyribonuclease VIII homolog (gi|7467238).
      
 0.850
ygbM
Putative endonuclease; Similar to E. coli orf, hypothetical protein (AAC75781.1); Blastp hit to AAC75781.1 (258 aa), 79% identity in aa 1 - 258; Belongs to the hyi family.
      
 0.727
ygbF
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75796.1); Blastp hit to AAC75796.1 (116 aa), 84% identity in aa 23 - 116.
     
 0.727
STM1033
Gifsy-2 prophage Clp protease-like protein; Similar to E. coli ATP-dependent proteolytic subunit of clpA-clpP serine protease, heat shock protein F21.5 (AAC73540.1); Blastp hit to AAC73540.1 (207 aa), 29% identity in aa 73 - 203; Belongs to the peptidase S14 family.
 
  
 0.716
STM0912
Fels-1 prophage protease subunits of ATP-dependent proteases; Similar to E. coli ATP-dependent proteolytic subunit of clpA-clpP serine protease; ClpP family members; heat shock protein F21.5 (AAC73540.1); Blastp hit to AAC73540.1 (207 aa), 29% identity in aa 73 - 203; Belongs to the peptidase S14 family.
 
  
 0.708
STM0911
Fels-1 prophage protein.
  
    0.703
lpfD
Long polar fimbrial operon protein; LPFD protein precursor. (SW:LPFD_SALTY).
      
 0.674
STM1032
Gifsy-2 prophage protein.
  
    0.661
STM0910
Fels-1 prophage protein.
  
    0.649
STM1031
Gifsy-2 prophage protein.
  
     0.646
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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