Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yhgEPutative inner membrane protein; Similar to E. coli putative transport (AAC76427.1); Blastp hit to AAC76427.1 (574 aa), 56% identity in aa 1 - 574. (569 aa)    
Predicted Functional Partners:
ygeD
Putative efflux protein; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell; Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
   
  
 0.861
STM4261
Putative inner membrane protein; Fusion of two hypothetical proteins; (gi|7467255) and (gi|7467255).
      
 0.859
yibP
Similar to E. coli putative membrane protein (AAC76637.1); Blastp hit to AAC76637.1 (427 aa), 91% identity in aa 1 - 427.
      
 0.858
pgtB
Protein for signal transmission; Member of the two-component regulatory system PgtB/PgtA that regulates the inducible phosphoglycerate transport system. Activates PgtA by phosphorylation.
   
  
 0.853
yobH
Putative outer membrane or exported.
      
 0.814
yfeK
Putative periplasmic protein; Hypothetical 13.3 Kda protein in pdxK-cysM intergenic region. (SW:YFEK_SALTY).
  
     0.744
srfC
ssrAB activated gene; Predicted coiled-coil structure; SrfC (gi|8347260).
      
 0.723
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase; This bifunctional enzyme catalyzes two consecutive reactions during ribonucleic acid degradation. Converts a 2',3'-cyclic nucleotide to a 3'-nucleotide and then the 3'-nucleotide to the corresponding nucleoside and phosphate; Belongs to the 5'-nucleotidase family.
   
  
 0.718
yfiK
Putative transport protein; Exporter of O-acetylserine (OAS) and cysteine; Belongs to the Rht family.
  
  
 0.709
csiE
Stationary phase inducible protein; Similar to E. coli orf, hypothetical protein (AAC75588.1); Blastp hit to AAC75588.1 (433 aa), 71% identity in aa 8 - 432.
  
     0.678
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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