STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhgGPutative cytoplasmic protein; May function as a transcriptional regulator that controls feoABC expression. (78 aa)    
Predicted Functional Partners:
feoB
Ferrous iron transport protein B; Probable transporter for a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
 
 
 0.999
feoA
Similar to E. coli ferrous iron transport protein A (AAC76433.1); Blastp hit to AAC76433.1 (75 aa), 96% identity in aa 1 - 75.
  
  
 0.988
fhuD
Hydroxamate-dependent iron uptake; ABC superfamily (bind _prot); similar to E. coli hydroxamate-dependent iron uptake, cytoplasmic membrane component (AAC73263.1); Blastp hit to AAC73263.1 (296 aa), 82% identity in aa 1 - 296.
      
 0.699
mntH
Manganese/divalent cation transport protein; H(+)-stimulated, divalent metal cation uptake system. Involved in manganese and iron uptake; Belongs to the NRAMP family.
      
 0.698
exbD
tonB-dependent uptake of B colicins; similar to E. coli uptake of enterochelin; tonB-dependent uptake of B colicins (AAC76041.1); Blastp hit to AAC76041.1 (141 aa), 93% identity in aa 1 - 141.
   
  
 0.681
hflB
ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.
      
 0.657
exbB
Uptake of enterochelin; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
   
  
 0.628
ygiM
Putative SH3 domain protein; Similar to E. coli orf, hypothetical protein (AAC76091.1); Blastp hit to AAC76091.1 (206 aa), 91% identity in aa 1 - 206.
      
 0.625
fepB
ABC superfamily (peri_perm); similar to E. coli ferric enterobactin (enterochelin) binding protein; periplasmic component (AAC73693.1); Blastp hit to AAC73693.1 (318 aa), 79% identity in aa 1 - 318.
   
  
 0.509
STM3508
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75365.1); Blastp hit to AAC75365.1 (296 aa), 67% identity in aa 1 - 296.
       0.432
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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