STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhgHPutative amidophosphoribosyltransferase; Could be involved in gluconate metabolism. (227 aa)    
Predicted Functional Partners:
smf
Putative protein involved in DNA uptake; Similar to E. coli orf, fragment 1 (AAC76311.1); Blastp hit to AAC76311.1 (253 aa), 66% identity in aa 1 - 248.
 
 
 0.924
yjeA
Putative pyruvate oxidase; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. Catalyzes the ATP-dependent activation of (R)-beta- lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF- P 'Lys-34' (Probable). Can also use L-alpha-lysine as a substrate, but probably with lower efficiency. Cannot aminoacylate tRNA(Lys) with lysine.
      
 0.892
ycaI
Putative recombination protein; Similar to E. coli orf, hypothetical protein (AAC73999.1); Blastp hit to AAC73999.1 (780 aa), 70% identity in aa 27 - 780.
 
  
 0.877
yifB
Putative magnesium chelatase, subunit ChlI; Hypothetical 55.0 Kda protein in pssR-ilLl intergenic region. (SW:YIFB_SALTY); Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.
 
  
 0.860
flk
Cell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion (T3S) system. Plays a role in hindering to flip the flagellar T3S specificity switch from the rod and hook-type substrates to filament-type substrates prior to hook-basal body (HBB) completion possibly by preventing interaction of FliK with FlhB.
      
 0.836
radC
Putative DNA repair protein; Associated with replication forks; similar to E. coli DNA repair protein (AAC76662.1); Blastp hit to AAC76662.1 (224 aa), 83% identity in aa 10 - 224; Belongs to the UPF0758 family. YicR subfamily.
 
    0.762
yraN
Putative endonuclease; Similar to E. coli orf, hypothetical protein (AAC76182.1); Blastp hit to AAC76182.1 (131 aa), 83% identity in aa 1 - 131; Belongs to the UPF0102 family.
 
    0.739
yhgI
Putative thioredoxin-like proteins and domain protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
     
 0.705
tyrA
Chorismate mutase T; Bifuctional; similar to E. coli chorismate mutase-T and prephenate dehydrogenase (AAC75649.1); Blastp hit to AAC75649.1 (373 aa), 95% identity in aa 1 - 372.
  
  
 0.686
nagA
Similar to E. coli N-acetylglucosamine-6-phosphate deacetylase (AAC73771.1); Blastp hit to AAC73771.1 (382 aa), 92% identity in aa 1 - 380.
  
    0.659
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.