STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM3517Putative DNA-damage-inducibile protein; Resembles dinJ; similar to E. coli damage-inducible protein J (AAC73330.1); Blastp hit to AAC73330.1 (86 aa), 83% identity in aa 1 - 86. (86 aa)    
Predicted Functional Partners:
STM3516
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC73329.1); Blastp hit to AAC73329.1 (92 aa), 78% identity in aa 1 - 91.
 
 
 0.997
dcm
Similar to E. coli DNA cytosine methylase (AAC75027.1); Blastp hit to AAC75027.1 (472 aa), 83% identity in aa 1 - 472.
      
 0.859
STM4450
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74636.1); Blastp hit to AAC74636.1 (95 aa), 67% identity in aa 1 - 94.
 
 
 0.712
STM1550
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74636.1); Blastp hit to AAC74636.1 (95 aa), 62% identity in aa 1 - 87.
 
 
 0.701
STM4030
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76117.1); Blastp hit to AAC76117.1 (138 aa), 45% identity in aa 19 - 138.
  
   
 0.604
rtcA
RNA 3'-terminal phosphate cyclase (with b3419); Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
  
    0.586
rtcB
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76446.1); Blastp hit to AAC76446.1 (408 aa), 87% identity in aa 1 - 408.
  
  
 0.551
vapC
Putative nucleic acid-binding protein; Toxic component of a type II toxin-antitoxin (TA) system. A site-specific tRNA-(fMet) endonuclease, it cleaves both charged and uncharged tRNA-(fMet) between positions 38 and 39 at the anticodon stem-loop boundary. Does not cleave tRNA(Met), tRNA(Arg2), tRNA(His), tRNA(Leu), tRNA(Phe) tRNA(Thr1), tRNA(Tyr) or tRNA(Val). Overexpression in E.coli inhibits translation, leads to loss of cell growth and degradation of tRNA(fMet), these effects are neutralized by expression of cognate antitoxin VapB. Expression also activates translation initiation at c [...]
 
   
 0.501
STM3778
Putative helix-turn-helix protein.
 
   
 0.474
STM4031
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76118.1); Blastp hit to AAC76118.1 (104 aa), 40% identity in aa 1 - 99.
  
  
 0.455
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.