STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM3549Putative inner membrane protein. (323 aa)    
Predicted Functional Partners:
ydcZ
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC74529.1); Blastp hit to AAC74529.1 (149 aa), 86% identity in aa 1 - 149.
     
  0.900
STM3550
Similar to E. coli putative hydrolase (AAC76404.1); Blastp hit to AAC76404.1 (292 aa), 28% identity in aa 24 - 289, 71% identity in aa 7 - 20.
 
    0.873
STM3548
Putative cytoplasmic protein; ORF 245 (gi|4456875).
 
    0.865
rbsK-2
Putative transcriptional regulator of sugar metabolism; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
    0.720
orf245
Putative cytoplasmic protein; ORF 245 (gi|4456875).
 
    0.573
STM4041
Putative inner membrane protein.
  
     0.525
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
    0.519
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
    0.516
yhhY
Putative transferase; Similar to E. coli orf, hypothetical protein (AAC76466.1); Blastp hit to AAC76466.1 (162 aa), 82% identity in aa 1 - 162.
 
    0.439
pyrD
Dihydro-orotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
    0.415
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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