Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
livFHigh-affinity branched-chain amino acid transporter; Component of the high-affinity branched-chain amino acid transport system. (237 aa)    
Predicted Functional Partners:
livM
High-affinity branched-chain amino acid transporter; Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane; Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily.
 
 0.999
livH
High-affinity branched-chain amino acid transporter; Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane; Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily.
 
 0.999
livG
High-affinity branched-chain amino acid transporter; Component of the high-affinity branched-chain amino acid transport system.
 
 
0.997
livK
High-affinity branched-chain amino acid transporter; This protein is a component of the leucine-specific transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids; Belongs to the leucine-binding protein family.
 
 
 0.996
livJ
High-affinity branched-chain amino acid transporter; This protein is a component of the leucine, isoleucine, valine, threonine transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids; Belongs to the leucine-binding protein family.
 
 
 0.991
STM3558
Homology to death -on-curing protein of phage P1.
  
    0.510
yhhV
Putative cytoplasmic protein; Putative antitoxin component of a toxin-antitoxin (TA) system; its cognate toxin is unknown.
       0.507
lnt
Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.
      
 0.444
hypB
Hydrogenase-3 accessory protein; Assembly of metallocenter; similar to E. coli guanine-nucleotide binding protein, functions as nickel donor for large subunit of hydrogenase 3 (AAC75769.1); Blastp hit to AAC75769.1 (290 aa), 94% identity in aa 1 - 290.
     
 0.439
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.429
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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