Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yhhLPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC76491.1); Blastp hit to AAC76491.1 (89 aa), 86% identity in aa 1 - 89. (90 aa)    
Predicted Functional Partners:
yhhF
Putative methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
 
    0.923
ygdD
Putative small membrane protein; Similar to E. coli orf, hypothetical protein (AAC75849.1); Blastp hit to AAC75849.1 (131 aa), 90% identity in aa 1 - 131.
   
  
 0.849
ybjO
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC73945.1); Blastp hit to AAC73945.1 (162 aa), 80% identity in aa 6 - 162.
      
 0.814
yfiH
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC75642.1); Blastp hit to AAC75642.1 (243 aa), 87% identity in aa 1 - 243; Belongs to the multicopper oxidase YfiH/RL5 family.
      
 0.726
ygdE
Putative SAM-dependent methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
      
 0.726
ycbY
Putative N6-adenine-specific DNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
   
  
 0.706
ybjF
Putative tRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
      
 0.691
ftsY
GTPase domain of cell division membrane protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
     
 0.651
apaG
Putative cytoplasmic protein; Not known; mutations in apaG/corD give a phenotype of low- level Co(2+) resistance. They also decrease Mg(2+) efflux but not influx via the CorA Mg(2+) transport system.
      
 0.649
ftsX
Putative integral membrane cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.646
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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