Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
uspAUniversal stress protein A; Required for resistance to DNA-damaging agents. (144 aa)    
Predicted Functional Partners:
ydaA
Putative universal stress protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
  
  
 0.961
uspB
Universal stress protein B; Involved in stationary-phase resistance to ethanol; similar to E. coli orf, hypothetical protein (AAC76519.1); Blastp hit to AAC76519.1 (111 aa), 95% identity in aa 1 - 111.
  
  
 0.932
ynaF
Similar to E. coli putative filament protein (AAC74458.1); Blastp hit to AAC74458.1 (168 aa), 90% identity in aa 25 - 168.
   
  
 0.913
ybdQ
Putative universal stress protein UspA and related nucleotide-binding protein; Similar to E. coli orf, hypothetical protein (AAC73708.1); Blastp hit to AAC73708.1 (142 aa), 89% identity in aa 1 - 142.
   
  
 0.910
yiiU
Putative cytoplasmic protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
  
 0.850
ompC
Outer membrane protein 1b (ib;c); Forms pores that allow passive diffusion of small molecules across the outer membrane.
  
  
 0.829
nmpC
New outer membrane protein; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family.
  
  
 0.794
ompF
Outer membrane protein 1a (ia;b;f), porin; Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2 (By similarity).
  
  
 0.779
yhcB
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76265.1); Blastp hit to AAC76265.1 (134 aa), 97% identity in aa 1 - 134.
  
    0.777
STM1530
Similar to E. coli putative outer membrane protein (AAC74459.1); Blastp hit to AAC74459.1 (377 aa), 61% identity in aa 2 - 377; Belongs to the Gram-negative porin family.
  
     0.767
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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