Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yhiQPutative SAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA. (252 aa)    
Predicted Functional Partners:
prlC
Oligopeptidase A; May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4).
 
  
 0.987
yafE
Putative methyltransferase in menaquinone/biotin biosynthesis; Similar to E. coli putative biotin synthesis protein (AAC73315.1); Blastp hit to AAC73315.1 (207 aa), 71% identity in aa 3 - 206.
   
  
 0.896
yihD
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76856.1); Blastp hit to AAC76856.1 (89 aa), 94% identity in aa 1 - 89.
     
 0.895
yafS
Putative SAM-dependent methyltransferase; Similar to E. coli orf, hypothetical protein (AAC73318.1); Blastp hit to AAC73318.1 (246 aa), 86% identity in aa 7 - 244.
 
  
 0.889
trmJ
Putative rRNA methylase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
 
  
 0.821
lasT
Putative tRNA/tRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
 
  
 0.757
bioC
Biotin biosynthesis; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
  
  
 0.734
yifE
Putative LysR type transcriptional regulator with pssR; Similar to E. coli orf, hypothetical protein (AAC77485.1); Blastp hit to AAC77485.1 (112 aa), 95% identity in aa 1 - 112; Belongs to the UPF0438 family.
      
 0.724
yhiP
Putative POT family peptide transport protein; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily.
   
  
 0.706
yfiF
Putative tRNA/rRNA methyltransferase; Similar to E. coli orf, hypothetical protein (AAC75634.1); Blastp hit to AAC75634.1 (345 aa), 87% identity in aa 1 - 345; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
  
 0.680
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.