STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM3602Putative gntR family regulatory protein; Similar to E. coli putative transcriptional regulator (AAC76400.1); Blastp hit to AAC76400.1 (265 aa), 28% identity in aa 27 - 260. (239 aa)    
Predicted Functional Partners:
STM3598
Similar to E. coli periplasmic L-asparaginase II (AAC75994.1); Blastp hit to AAC75994.1 (348 aa), 46% identity in aa 22 - 348.
     
 0.921
STM4068
Putative gntR family regulatory protein; Similar to E. coli transcriptional regulator of succinylCoA synthetase operon (AAC73824.1); Blastp hit to AAC73824.1 (240 aa), 28% identity in aa 5 - 220.
  
    0.778
phnA
Putative alkylphosphonate uptake protein in phosphonate metabolism; Similar to E. coli orf, hypothetical protein (AAC77069.1); Blastp hit to AAC77069.1 (111 aa), 96% identity in aa 1 - 111.
      
 0.768
nadR
Trifunctional protein; This enzyme has three activities: DNA binding, nicotinamide mononucleotide (NMN) adenylyltransferase and ribosylnicotinamide (RN) kinase. The DNA-binding domain binds to the nadB operator sequence in an NAD- and ATP-dependent manner. As NAD levels increase within the cell, the affinity of NadR for the nadB operator regions of nadA, nadB, and pncB increases, repressing the transcription of these genes. The RN kinase activity catalyzes the phosphorylation of RN to form nicotinamide ribonucleotide. The NMN adenylyltransferase activity catalyzes the transfer of the A [...]
   
  
 0.740
lldR
Putative transcriptional GntR family regulator for lct operon; Similar to E. coli transcriptional regulator (AAC76628.1); Blastp hit to AAC76628.1 (258 aa), 86% identity in aa 1 - 258.
  
    0.722
pdhR
Transcriptional repressor for pyruvate dehydrogenase complex (GntR family); Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd.
  
    0.719
phnW
2-aminoethylphosphonate transport; Involved in phosphonate degradation.
     
 0.676
STM1541
Putative gntR family regulatory protein; Similar to E. coli regulator for uxu operon (AAC77280.1); Blastp hit to AAC77280.1 (257 aa), 31% identity in aa 8 - 229.
  
    0.658
STM3084
Putative gntR family regulatory protein; Similar to E. coli regulator for uxu operon (AAC77280.1); Blastp hit to AAC77280.1 (257 aa), 39% identity in aa 8 - 247.
  
    0.628
gntR
Transcriptional repressor gnt-I; gntUKR; GalR/LacI family; similar to E. coli regulator of gluconate (gnt) operon (AAC76463.1); Blastp hit to AAC76463.1 (313 aa), 97% identity in aa 1 - 304.
  
  
 0.584
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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