STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM3605Putative phage endolysin. (118 aa)    
Predicted Functional Partners:
STM1868A
Lytic enzyme.
      
 0.898
STM1028
Gifsy-2 prophage lysozyme; Similar to E. coli bacteriophage lambda lysozyme homolog (AAC73656.1); Blastp hit to AAC73656.1 (165 aa), 40% identity in aa 35 - 161.
      
 0.892
STM2715
Fels-2 prophage protein; Probable prophage lysozyme; similar to E. coli bacteriophage lambda lysozyme homolog (AAC73656.1); Blastp hit to AAC73656.1 (165 aa), 36% identity in aa 35 - 163.
      
 0.892
yajD
Putative cytoplasmic protein; Hypothetical 12.6 Kda protein in secF-tsx intergenic region. (SW:YAJD_SALTY); Belongs to the HNH nuclease family.
     
 0.891
yciI
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74333.1); Blastp hit to AAC74333.1 (130 aa), 91% identity in aa 33 - 130.
      
 0.834
mazG
Putative pyrophosphatase; Similar to E. coli orf, hypothetical protein (AAC75823.1); Blastp hit to AAC75823.1 (263 aa), 93% identity in aa 2 - 263.
      
 0.764
STM1009
Gifsy-2 prophage exodeoxyribonuclease; Exodeoxyribonuclease VIII homolog (gi|7467238).
      
 0.761
orf48
Amino acid permease YeeF like protein (gi|1526981).
      
 0.698
vacJ
Similar to E. coli lipoprotein precursor (AAC75406.1); Blastp hit to AAC75406.1 (251 aa), 94% identity in aa 1 - 251.
      
 0.672
thyA
Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
      
 0.657
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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