STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhjNPutative cellulose synthase; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family. (766 aa)    
Predicted Functional Partners:
bcsC
endo-1,4-D-glucanase; Hydrolyzes carboxymethylcellulose; Belongs to the glycosyl hydrolase 8 (cellulase D) family.
  
 0.999
yhjO
Glycosyltransferase; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multicellular behavior (rdar morphotype). Coexpression of cellulose and thin aggregative fimbriae leads to a hydrophobic network with tightly packed cells embedded in a highly inert matrix.
 0.999
yhjQ
Putative ATPase involved in chromosome partitioning; Essential for cellulose biosynthesis. May play a role in subcellular localization of an active cellulose biosynthesis apparatus at the bacterial cell pole (By similarity); Belongs to the BcsQ family.
 
  
 0.997
yhjT
Putative inner membrane protein; Required for cellulose biosynthesis. Belongs to the BcsF family.
     
 0.989
yhjL
Putative TPR-repeat-containing protein; Required for maximal bacterial cellulose synthesis. Belongs to the AcsC/BcsC family.
 
 0.985
yhjR
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76560.1); Blastp hit to AAC76560.1 (62 aa), 76% identity in aa 1 - 60.
  
  
 0.984
yhjS
Putative cytoplasmic protein; Required for cellulose biosynthesis. May have protease activity , but BcsA is not targeted. Binds bis-(3'-5') cyclic diguanylic acid (c-di-GMP) ; Belongs to the BcsE family.
  
  
 0.979
yhjU
Putative inner membrane protein; Required for cellulose biosynthesis.
  
  
 0.951
celB
PTS family sugar specific enzyme II for cellobiose, arbutin, and salicin; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
      
 0.764
wcaD
Similar to E. coli putative colanic acid polymerase (AAC75117.1); Blastp hit to AAC75117.1 (405 aa), 93% identity in aa 1 - 404.
      
 0.696
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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