Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yhjSPutative cytoplasmic protein; Required for cellulose biosynthesis. May have protease activity , but BcsA is not targeted. Binds bis-(3'-5') cyclic diguanylic acid (c-di-GMP) ; Belongs to the BcsE family. (523 aa)    
Predicted Functional Partners:
yhjT
Putative inner membrane protein; Required for cellulose biosynthesis. Belongs to the BcsF family.
  
 
 0.999
yhjU
Putative inner membrane protein; Required for cellulose biosynthesis.
  
 
 0.997
yhjQ
Putative ATPase involved in chromosome partitioning; Essential for cellulose biosynthesis. May play a role in subcellular localization of an active cellulose biosynthesis apparatus at the bacterial cell pole (By similarity); Belongs to the BcsQ family.
  
 
 0.995
yhjO
Glycosyltransferase; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multicellular behavior (rdar morphotype). Coexpression of cellulose and thin aggregative fimbriae leads to a hydrophobic network with tightly packed cells embedded in a highly inert matrix.
  
 
 0.993
yhjN
Putative cellulose synthase; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.
  
  
 0.982
yhjR
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76560.1); Blastp hit to AAC76560.1 (62 aa), 76% identity in aa 1 - 60.
  
 
 0.979
bcsC
endo-1,4-D-glucanase; Hydrolyzes carboxymethylcellulose; Belongs to the glycosyl hydrolase 8 (cellulase D) family.
  
  
 0.976
csgD
Putative transcriptional regulator; Necessary for transcription of the csgAB operon. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription (By similarity).
   
  
 0.729
bglX
Periplasmic beta-D-glucoside glucohydrolase; Periplasmic beta-glucosidase precursor. (SW:BGLX_SALTY); Belongs to the glycosyl hydrolase 3 family.
      
 0.720
dgcQ
Putative inner membrane protein; Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria. Involved in the regulation of cellulose production (By similarity).
      
 0.717
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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