Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yhjVSimilar to E. coli putative transporter protein (AAC76564.1); Blastp hit to AAC76564.1 (423 aa), 87% identity in aa 5 - 423. (432 aa)    
Predicted Functional Partners:
yehU
Putative sensor/kinase in regulatory system; Similar to E. coli putative 2-component sensor protein (AAC75187.1); Blastp hit to AAC75187.1 (561 aa), 91% identity in aa 1 - 561.
   
  
 0.683
yrbL
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76239.1); Blastp hit to AAC76239.1 (210 aa), 77% identity in aa 1 - 210.
  
 
 0.566
STM3624A
Cystathionine gamma-synthase.
     
 0.531
ygiW
Putative outer membrane protein; Similar to E. coli orf, hypothetical protein (AAC76060.1); Blastp hit to AAC76060.1 (130 aa), 89% identity in aa 1 - 130.
  
     0.529
dps
Stress response DNA-binding protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
    
   0.504
adiY
Transcriptional activator of adiA; AraC/XylS family; similar to E. coli putative ARAC-type regulatory protein (AAC77077.1); Blastp hit to AAC77077.1 (253 aa), 79% identity in aa 1 - 253.
  
     0.461
yjiW
Putative SOS response protein; Involved in the degradation and recycling of damaged RNA. It is itself a target for degradation by the ATP-dependent protease Lon. Belongs to the SymE family.
      
 0.450
yhjU
Putative inner membrane protein; Required for cellulose biosynthesis.
   
  
 0.431
yccD
Putative cytoplasmic protein; Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ.
  
     0.430
STM3022
Similar to E. coli putative transporter protein (AAC75884.1); Blastp hit to AAC75884.1 (409 aa), 90% identity in aa 1 - 408.
  
   
0.424
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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